Role of ascetic fluid culture and lipopolysaccharide binding protein in diagnosis of spontaneous bacterial peritonitis in cirrhotic patients /
دور زرع سائل الحبن و البروتين الرابط لعديد السكاريد الشحمى فى التهاب البريتوان العفوى عند مرض تشمع الكبد
Ahmed Mohamed Shennawy ; Supervised Reda Amer , Ahmed Amin , Heba Sharaf Eldin
- Cairo : Ahmed Mohamed Shennawy , 2014
- 120 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
Many studies, suggest that ascitic fluid cultures have low yield with respect to diagnosis and deciding management of patients with ascites. In addition, positive culture and sensitivity results obtained from emergency department have not been shown to result in appropriate adjustment of antibiotic therapy (chinnock et al, 2011), serum lipopolysaccharide-binding protein (LBP) is increased in a subset of non-infected ascitic cirrhotic patients, a finding previously related to bacterial passage from the gut to the circulation without overt infection (chinnock et al, 2009), some studies showed that the level of serum LBP was significantly higher in cirrhotic ascitic patients with SBP than in the cirrhotic ascitic patients without SBP (Tang NY, 2012). The objectives of our work to evaluate the value of serum LBP and ascitic fluid culture in cirrhotic patients assumed to have SBP. This study included 85 patients who have liver cirrhosis, they were 48 males and 37 females, who were divided into two groups, group A: 50 patients with ascites and group B: 35 ascitic patients assumed to have SBP presented with abdominal pain, fever, absent bowel sound, diarrhia, unexplained hepatic encephalopathy
Ascitic fluid culture Liver cirrhosis Serum lipopolysaccharide binding protein