TY  - BOOK
AU  - Bassant Morsy Sayed
AU  - Amani Nabil Shafik , 
AU  - Fatma Ahmed Elbatrawi , 
AU  - Nahed Mahmoud Moussa , 
TI  - Study of the osteogenic and cardiovascular effects of mono and combined administration of growth hormone and simvastatin to ovariectomized rats / 
PY  - 2014///
CY  - Cairo : 
PB  - Bassant Morsy Sayed , 
KW  - Cardiovascular
KW  - Growth hormone and simvastatin
KW  - Ovariectomized
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pharmacology; Issued also as CD
N2  - Aim: The aim of the present work was to investigate the possible role of  growth hormone and simvastatin alone and combined on osteogenic bone  changes induced by ovariectomy in rats. Furthermore, study the  cardioprotective effects of each drug on myocardial ischemia induced by  isoprenaline. Conclusion: It could be concluded from the present work that both growth  hormone and simvastatin have antiosteoporotic effect as was evident by  histopathological improvement in cortical and trabecular bone thickness  more with simvastatin.  The present study also demonstrated ischemic cardioprotective  potential of growth hormone and simvastatin by attenuating isoprenaline- induced ST segment elevations, decreasing previously elevated heart rate,  normalization of blood pressure alterations and improvement of altered  histopathological changes of the heart tissue more with simvastatin
ER  -