Asmaa Mohamed Fteah Abdelaziz <br/><br/>
Study of xeroderma pigmentosum Ccomplemetation group D (XPD) codon 751 polymorphism in hepatocellular carcinoma /  
 دراسة الأشكال المتعددة للجين إكس بي دي 751 في حالات سرطان الكبد الخلوي 
Asmaa Mohamed Fteah Abdelaziz ; Supervised Nevine Ezz Eldin Elabd , Mona Mohamed Hassan , Asmaa Mohamed Kamal 
 - Cairo :   Asmaa Mohamed Fteah Abdelaziz ,   2014 
 - 141 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology 
<br/><br/> Background: Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver. The molecular determinants of the HCC progression are still under investigation. The Xeroderma Pigmentosum Complementation Group D (XPD) is a major DNA repair gene which plays a vital role in Nucleotide Excision repair (NER) which is reported to be associated with risk of several cancers. Genetic polymorphisms in XPD gene may influence individual variations in DNA repair capacity, which may be associated with increased risk of HCC. OBJECTIVE: The aim of this study was to investigate the association between XPD/ERCC2  Lys751Gln (A/C) gene polymorphism (rs 13181) and the incidence of HCC in Egyptian patients   
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<br/><br/><label>Subjects--Index Terms: </label>Gene Polymorphism  HCC   XPD Lys751Gln (A/C)