TY  - BOOK
AU  - Asmaa Mohamed Fteah Abdelaziz
AU  - Asmaa Mohamed Kamal , 
AU  - Mona Mohamed Hassan , 
AU  - Nevine Ezz Eldin Elabd , 
TI  - Study of xeroderma pigmentosum Ccomplemetation group D (XPD) codon 751 polymorphism in hepatocellular carcinoma / 
PY  - 2014///
CY  - Cairo : 
PB  - Asmaa Mohamed Fteah Abdelaziz , 
KW  - Gene Polymorphism
KW  - HCC
KW  - XPD Lys751Gln (A/C)
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology; Issued also as CD
N2  - Background: Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver. The molecular determinants of the HCC progression are still under investigation. The Xeroderma Pigmentosum Complementation Group D (XPD) is a major DNA repair gene which plays a vital role in Nucleotide Excision repair (NER) which is reported to be associated with risk of several cancers. Genetic polymorphisms in XPD gene may influence individual variations in DNA repair capacity, which may be associated with increased risk of HCC. OBJECTIVE: The aim of this study was to investigate the association between XPD/ERCC2  Lys751Gln (A/C) gene polymorphism (rs 13181) and the incidence of HCC in Egyptian patients
UR  - http://172.23.153.220/th.pdf
ER  -