Doaa Mamdouh Aly Ahmad Abubakr <br/><br/>
The role of intercellular adhesion molecule -1 gene polymorphism in the development of cardiovascular disease in egyptian patients with end-stage renal disease /  
 دور تعدد الاشكال الجينى فى الجين المسئول عن جزىء الالتصاق بين الخلايا رقم 1فى حدوث أمراض القلب و الأوعية الدموية فى المرضي المصريين المصابين بالفشل الكلوى المزمن 
Doaa Mamdouh Aly Ahmad Abubakr ; Supervised Fatma Ahmed Fathy Elmougy , Afaf Ahmed Abdelhady , Rania Kamal Darwish  
 - Cairo :   Doaa Mamdouh Aly Ahmad Abubakr ,   2014 
 - 133 P. :   charts ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of in Clinical and Chemical Pathology 
<br/><br/> Background: End-stage renal disease is the most serious consequence of chronic kidney disease. The commonest cause of mortality in end-stage renal disease is cardiovascular diseases. Thus, the pathogenesis of cardiovascular diseases has been extensively studied focusing on genetic factors which have a major role. One of these genetic factors is Intercellular adhesion molecule-1(ICAM-1) gene, particularly single nucleotide polymorphism in ICAM-1 gene called K469 (rs5498). Objective: To study if K469E polymorphism of the ICAM-1 gene is associated with increased cardiovascular disease risk in Egyptian patients with end-stage renal disease 
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<br/><br/><label>Subjects--Index Terms: </label>Cardiovascular diseases  End-stage renal disease  ICAM