TY - BOOK AU - Doaa Mamdouh Aly Ahmad Abubakr AU - Afaf Ahmed Abdelhady , AU - Fatma Ahmed Fathy Elmougy , AU - Rania Kamal Darwish , TI - The role of intercellular adhesion molecule -1 gene polymorphism in the development of cardiovascular disease in egyptian patients with end-stage renal disease / PY - 2014/// CY - Cairo : PB - Doaa Mamdouh Aly Ahmad Abubakr , KW - Cardiovascular diseases KW - End-stage renal disease KW - ICAM N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of in Clinical and Chemical Pathology; Issued also as CD N2 - Background: End-stage renal disease is the most serious consequence of chronic kidney disease. The commonest cause of mortality in end-stage renal disease is cardiovascular diseases. Thus, the pathogenesis of cardiovascular diseases has been extensively studied focusing on genetic factors which have a major role. One of these genetic factors is Intercellular adhesion molecule-1(ICAM-1) gene, particularly single nucleotide polymorphism in ICAM-1 gene called K469 (rs5498). Objective: To study if K469E polymorphism of the ICAM-1 gene is associated with increased cardiovascular disease risk in Egyptian patients with end-stage renal disease UR - http://172.23.153.220/th.pdf ER -