TY  - BOOK
AU  - Walied Khalid Elhossary
AU  - Doaa Mohammed Abdelatty , 
AU  - Hassan Ahmed Elgaarem , 
AU  - Iman Mohamed Hamza , 
TI  - Prevalence and genetic background of metronidazole resistance of helicobacter pylori strains in Egyptian patients / 
PY  - 2014///
CY  - Cairo : 
PB  - Walied Khalid Elhossary , 
KW  - Helicobacter pylori
KW  - Metronidazole resistance
KW  - rdxA gene
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine; Issued also as CD
N2  - Background & aims: the molecular mechanisms of metronidazole resistance are mediated by inactivation of an oxygen-insensitve NADPH  nitroreductase (rdxA). therefore, this study was initated to determine metronidazole resistance among H.pylori isolates in Egypt by detection of rdxA gene mutation . Patients and Methods: 100 patients included who presented to the endoscopy unit kasr Al Aini hospital where upper GI endoscopy with gastric biopsies (body and antrum) were done. The specimens were tested for the presence of H. pylori by PCR (Hp 16S). Then, positive biopsies of H. pylori will be tested for the presence of metronidazole resistance gence (rdxA gene mutation) by PCR
ER  -