TY  - BOOK
AU  - Nessma Hassan Hassan Ahmed
AU  - Hassan Abdelhalim Hassan Amer , 
AU  - Mohsen Ahmed Wasfy , 
TI  - Chemopreventive role of panax ginseng and grape seed extract against thallium toxicity in rats / 
PY  - 2014///
CY  - Cairo : 
PB  - Nessma Hassan Hassan Ahmed , 
KW  - Grape seed
KW  - Oxidative stress
KW  - Panax ginseng
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Biochemistry and Chemistry of Nutrition; Issued also as CD
N2  - Procyanidins are natural botanic polyphenols extracted from grape seeds, with bioactivities such as antioxidation, free radical elimination and  cell proliferation stimulation. Ginseng has long been known to possess a variety of beneficial pharmacological effects, such as enhancement of immunity, and hyperlipidaemia and diabetes prevention. Oxidative stress has been proven to be involved in thallium-induced toxicity. Therefore, the  present study was undertaken to examine the antioxidant potential of panax ginseng and grape seed against the toxicity of thallium in male rats. The  results revealed that oral administration of 150 g/ kg bwt of grape seed and 3 mg/ kg.bwt of panax ginseng inhibited the increase in lipid peroxidation caused by thallium, reduced the elevation of serum LDH, ALT and AST activities, MDA levels and creatinine with improvement in CAT activity that  induced by thallium. They also increased the activities of antioxidant  enzymes (SOD, and GSH-Px), GSH and total protein levels. Therefore, the  present results suggested that grape seed and panax ginseng exerts a protective effect against thallium toxicity
UR  - http://172.23.153.220/th.pdf
ER  -