Fatma Mostafa Ahmed Elelimy <br/><br/>
Study of growth differentiation factor 15 level in patients with beta thalassemia major /  
 فى حالات انيميا البحر المتوسط GDF15دراسة  
Fatma Mostafa Ahmed Elelimy ; Supervised Mona Hassan Eltagy , Mona Mohamed Hamdy , Nadia Ibrahim Sewilam 
 - Cairo :   Fatma Mostafa Ahmed Elelimy ,   2014 
 - 103 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics 
<br/><br/> Background:The thalassemia syndromes represent the most common causes of ineffective erythropoiesis . The increased but ineffective erythropoiesis resulting in tissue iron overload induces numerous endocrine diseases, hepatic cirrhosis, cardiac failure and even death . Objectives: To study GDF15 levels in Ý- thalassemia major patients and to correlate its level to their iron status and different clinical and  laboratory disease parameters. Conclusion:GDF15 level in our study represent a first step for its use as biomarker in thalassemia patients although future studies may be needed before its routine use  
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<br/><br/><label>Subjects--Index Terms: </label>GDF15 gene Growth Differentiation Factor 15 Thalassemia major