TY - BOOK AU - Fatma Mostafa Ahmed Elelimy AU - Mona Hassan Eltagy , AU - Mona Mohamed Hamdy , AU - Nadia Ibrahim Sewilam , TI - Study of growth differentiation factor 15 level in patients with beta thalassemia major / PY - 2014/// CY - Cairo : PB - Fatma Mostafa Ahmed Elelimy , KW - GDF15 gene KW - Growth Differentiation Factor 15 KW - Thalassemia major N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD N2 - Background:The thalassemia syndromes represent the most common causes of ineffective erythropoiesis . The increased but ineffective erythropoiesis resulting in tissue iron overload induces numerous endocrine diseases, hepatic cirrhosis, cardiac failure and even death . Objectives: To study GDF15 levels in Ý- thalassemia major patients and to correlate its level to their iron status and different clinical and laboratory disease parameters. Conclusion:GDF15 level in our study represent a first step for its use as biomarker in thalassemia patients although future studies may be needed before its routine use UR - http://172.23.153.220/th.pdf ER -