TY  - BOOK
AU  - Ahmed Mohammed Abdelhaleem
AU  - Magdy Aly Amin , 
AU  - Ramy Karam Aziz , 
TI  - Virulence factors of extended spectrum Beta-lactamase-producing gram-negative clinical isolates / 
PY  - 2015///
CY  - Cairo : 
PB  - Ahmed Mohammed Abdelhaleem , 
KW  - ctx
KW  - Extended spectrum
KW  - New variants
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology; Issued also as CD
N2  - The rapid emergence of microbial strains that are resistant to almost every  existing antibiotic, often described as 2superbugs3, is a serious threat to human health,  with the eventual risk of depletion of all antibiotic choices against some bacterial  pathogens by the next decade. Escherichia coli (E.coli) is particularly known for its  genomic plasticity and its subsequent ability to horizontally acquire novel genetic  characters, including antibiotic resistance, especially in the hospital environment. Major  outbreaks of extended spectrum beta lactamase-producing (ESBL) E.coli (ESBLEC) have  been reported in Egypt and other countries. Because of the difficulty to track the spread  of antibiotic resistance contributed by closely related genes, this study was designed to  investigate the outbreaks of ESBL among E. coli clinical isolates. One hundred ninety  eight clinical isolates were collected from the National Cancer Institute, Qasr El-Ainy,  and Abu-El-Rish Children Hospital in Cairo-Egypt, and their antibiotic sensitivity was  screened by the Kirby Bauer disk diffusion method.
ER  -