TY  - BOOK
AU  - Shaimaa Shaheen Mohammed
AU  - Mohammed Eltokhy , 
AU  - Omar Amin Alserafy , 
AU  - Randa Shawky Deif , 
TI  - Cognitive impairment and magnetic  resonance diffusion tensor imaging  (MRDTI) of the brain in multiple sclerosis / 
PY  - 2014///
CY  - Cairo : 
PB  - Shaimaa Shaheen Mohammed , 
KW  - Cognitive dysfunction
KW  - Diffusion tensor MRI
KW  - Multiple sclerosis
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Neurology; Issued also as CD
N2  - Cognitive impairment is a common concomitant  of multiple sclerosis (MS) at both the earlier and later stages of the  disease. Objective: to study the pattern of cognitive impairment in various  types of MS and its correlation to the results of conventional MRI (c  MRI) and diffusion tensor MRI (DTMRI) of the brain. Results: a  significant difference was found between cases and control in most of  cognitive function tests. Significant difference was found between RRMS  & SPMS in cognitive function test and DTMRI brain results (for corpus  callosum and temporal lobe) being severe in SPMS patients. Significant  difference was found between RRMS and SPMS in c MRI results as  regards to brain atrophy being severe in SPMS patients. Conclusion:  cognitive dysfunction and brain atrophy occurs early in MS. Cognitive  dysfunction was more severe in SPMS than in RRMS patients. DTI brain  of NAWM was correlated with cognitive dysfunction in MS especially in  regions of corpus callosum, temporal & prefrontal lobes
UR  - http://172.23.153.220/th.pdf
ER  -