TY - BOOK AU - Eman Omar Rasekh AU - Alaa Mohamed Elhadad , AU - Azza Mahmoud Kamel , AU - Heba Sayed Moussa , TI - Fusion gene transcript levels at diagnosis and their kinetics in response to therapy as prognostic indicators in acute lymphoblastic leukemia : : Part of conjoint project with St. Jude Children Cancer Research Hospital / PY - 2015/// CY - Cairo : PB - Eman Omar Rasekh , KW - ALL KW - MRD KW - RQ-PCR N1 - Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology; Issued also as CD N2 - Aim of work: In this study we aim to evaluate the level of fusion gene as well as log reduction in their level at 2 weeks after starting induction chemotherapy. Patients with chromosomsal translocations will be tested for: Transcription level at diagnosis as well as for the kinetics of transcription reduction during therapy. The findings will be correlated to the achievement of complete remission, occurrence of relapse and survival data. The final aim is to verify if the transcript level at diagnosis has an impact on outcome. Also to verify if we can detect at an early point of time, namely day 14, the response to therapy UR - http://172.23.153.220/th.pdf ER -