TY  - BOOK
AU  - Kholoud Ahmed Yousef Alhabashy
AU  - Hesham Salem Sharaf Eldin , 
AU  - Mamdouh Reda Rezk , 
AU  - Safa{u2019}a Mohamed Riad , 
TI  - Study of some gastrointestinal tract  drugs safe during pregnancy / 
PY  - 2015///
CY  - Cairo : 
PB  - Kholoud Ahmed Yousef Alhabashy , 
KW  - Diodohydroxyquin
KW  - Metronidazole
KW  - Spectrophotometry
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry; Issued also as CD
N2  - Recently multicomponent formulations have gained importance due to patient{u2019}s appliance,  synergistic effects, multiple action and fast onset of action. Thus, simultaneous estimation of  co-formulated drugs is an important part in the field of pharmacy as it cancels effort and time  of extraction, separation and gets accurate and precise results.This thesis is concerned with the quantitative determination of some pregnancy safe  drugs, namely, metronidazole, diiodohydroxyquin, omeprazole, tinidazole and clarithromycin in raw materials, in their mixtures and in their binary and/or tertiary pharmaceutical  formulations. Among the techniques adopted for analysis are; Spectrophotometric methods including; second derivative, third derivative, derivative ratio spectra, mean centering, isosbestic point method, ratio difference  and ratio subtraction coupled with extended ratio subtraction methods. Chromatographic methods including: HPLC and TLC-densitometric methods.  Potentiometric method; ion selective electrode method based on precipitation  technique with phosphotungestic and phosphomolybdic acids
UR  - http://172.23.153.220/th.pdf
ER  -