TY  - BOOK
AU  - Sherehan Mohamed Ibrahim Eldesoky
AU  - Dalaal Moustafa Abdallah , 
AU  - Ezz Eldin Eldenshary , 
TI  - Effect of pioglitazone alone or in combination with some natural products in fructose - induced metabolic syndrome in Rats / 
PY  - 2015///
CY  - Cairo : 
PB  - Sherehan Mohamed Ibrahim Eldesoky , 
KW  - Metabolic syndrome
KW  - Oxidative stress
KW  - Receptors for advanced glycated end products
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology; Issued also as CD
N2  - Metabolic syndrome (MetS) is mainly mediated by disruptions of prooxidant/antioxidant as well as inflammatory status. This study aimed  to test the potential anti - MetS effects of pioglitazone (PIO), methyl sulfonyl methane (MSM), geraniol (GO), as well as the combination of MSM or GO with PIO low dose. Rats were divided into 8 groups; the control group, the MetS group, and two groups received PIO (5 and 10  mg/Kg), MSM group (400 mg/Kg), GO group (250 mg / Kg), and two groups were given PIO low dose combined with MSM and GO. All drugs  were given orally for four weeks after 16 weeks administration of (10%) fructose solution to induce MetS. Administration of the aforementioned treatments showed an improvement in most of MetS criteria. These were signified by reduction in liver, visceral, and epididymal fat indices as well as body weight
UR  - http://172.23.153.220/th.pdf
ER  -