TY - BOOK AU - Moataz Abdalla Yehia AU - Mamdouh Reda Rezk , AU - Mohamed Abdalla Elsayed , AU - Mohamed Abdelkawy Ibrahim , TI - Analytical study for tadalafil (CialisĀ®) and equivalent compounds / PY - 2015/// CY - Cairo : PB - Moataz Abdalla Yehia , KW - CialisĀ® KW - Equivalent compounds KW - Tadalafil N1 - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry; Issued also as CD N2 - Four different stability indicating assay methods were developed and validated for the determination of (tadalafil, sildenafil and terazosin) in the presence of its degradation product. The first and second methods was based on the derivative and derivative ratio spectrophotometric technique using acetonitrile: water mixtrure {u2160}:{u2160} for tadalafil and methanol as a solvent for both sildenafil and terazosin. In the third method, we used TLC - densitometric technique using high performance thin - layer chromatography plates with a developing system consisting of {chloroform: acetone: ammonia (9: 1: 0.1, by volume)}, {chloroform: toluene: ethanol: acetic acid(3: 3: 4: 0.1, by volume)} and choloroform: acetone: ammonia 6: 4: 0.1, by voiumes UR - http://172.23.153.220/th.pdf ER -