Noha Salah Eldein Elsayed Ali Soliman <br/><br/>
Evaluation of Ý-lactam and aminoglycosides synergistic effect on multidrug resistant pseudomonas /  
 تقييم تأثير التآزر بين العقار من نوع البيتالاكتام مع الأمينوجليكوزايد على ميكروب السودوموناس 
Noha Salah Eldein Elsayed Ali Soliman ; Supervised Mona Abdelaziz Wassef , Maha Mohammed Gaafar , Dina Mohammed Hassan 
 - Cairo :   Noha Salah El-Dein El-Sayed Ali Soliman ,   2015 
 - 153 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology  
<br/><br/> Multidrug resistant Pseudomonas is one of the rapidly spreading bacteria causing infections with serious outcomes due to limited therapeutic options. Rapid spread of multidrug resistant bacteria (MDR) has become an emerging threat and a matter of concern worldwide.Our work aimed to screen for carbapenem resistance in 250 isolates of MDR Pseudomonas, evaluate the synergistic effect of Ý-lactam and aminoglycoside combination by using E-test in 50 selected carbapenem resistant MDR Pseudomonas isolates and investigate the role of plasmid transfer in spread of resistance.The distribution of the MDR Pseudomonas showed that the majority were encountered from ICU (47.6%) compared to inpatient wards (43.2%). Among different samples showed that the highest prevalence were in sputum (46.8%), followed by urine (26.8%), pus (21.6%) while the samples with the lowest prevalence were blood (4%) and ear discharge (2.8%) 
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<br/><br/><label>Subjects--Index Terms: </label>Aminoglycosides Pseudomonas Ý-Lactam