TY - GEN AU - Ghada Mohamed Nasr Radwan AU - Christopher Loffredo , AU - Omima Kamel , AU - Salwa Abd El Azeem , TI - Role of Behavioral and Genetic Factors in determining Tobacco - induced Harm in Male Smokers / PY - 2006/// CY - Cairo : PB - Ghada Mohamed Nasr Radwan , KW - Addiction KW - Micronuclie KW - Qalyubia KW - Smoking N1 - Thesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Community Medicine; Issued also as CD N2 - Despite the rapidly spreading epidemic of tobacco related diseases , little is known of the genetic contribution to current levels of cigarette consumption and nicotine addiction in EgyptThe dopamine D2 receptor gene has been previously suggested to be associated with impulsive / addictive / compulsive behaviorIn the present work we investigated the relationship between the dopamine receptor gene DRD2 polymorphism to tobacco behaviors , addiction and subsequent tobacco harm (as measured by exhaled CO and micronuclei in exfoliated buccal cells) in a cross sectional study of 389 Egyptian male current smokers UR - http://172.23.153.220/th.pdf ER -