The value of dynamic contrast-enhanced mri in the diagnosis and management of triple negative breast cancer /
قيمة التصوير بالرنين المغناطيسي الديناميكي بالصبغة في تشخيص وعلاج سرطان الثدي السلبي الثلاثي
Liza Omer Salem Daiban ; Supervised Rasha Mohammed Kamal , Heba Allah Mounir Azzam
- Cairo : Liza Omer Salem Daiban , 2015
- 225 P. : facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine- Department of Radio-diagnosis
Breast cancer (BC) is by far the worlds most common cancer among women, and it is the most common cause of cancer related death in women worldwide. Triple negative breast cancer (TNBC) is a subtype of breast cancer that lacks expression of estrogen receptors (ER), progesterone receptors (PR) and human epidermal growth factor receptor 2 (HER2). TNBC is characterized by distinct clinical, pathological features and don't respond to endocrinal therapy or targeted agents .Imaging for TNBC represents a diagnostic challenge to breast radiologists, and the aim of this work is to assess the MRI features of TNBC in comparison to other breast cancer subtypes and to validate its impact on management. Contrast-enhanced MRI is an accurate assessment of tumor response after Neo-Adjuvant Chemotherapy and should be incorporated in the evaluation of all patients with TNBC
Dynamic Contrast-Enhanced MRI TNBC Triple Negative Breast Cancer