TY  - BOOK
AU  - Nora Mohammed Hussein 
AU  - Fatma Ahmed Fathi El Mogy , 
AU  - Laila Hussein Mohammed , 
AU  - Nermin Ramy Mohamed Kamel , 
TI  - The influence of phototherapy on serum cytokine concentrations in newborn infants / 
PY  - 2015///
CY  - Cairo : 
PB  - Nora Mohammed Hussein , 
KW  - Interleukin
KW  - NNJ
KW  - Pototherapy
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD
N2  - Neonatal jaundice in the first week of life is a common problem in newborns.The most important intervention for infants with severe  hyperbilirubinemia is to initiate phototherapy without delay. Although  phototherapy is the standard treatment for neonatal hyperbilirubinemia, it may lead  to potential side effects such as retinal degeneration, diarrhea, dehydration, and  skin rash. Phototherapy treatment can affect the function of the immune system in newborns via alterations in cytokine production. Objectives:In our study we  hypothized that phototherapy can affect the level of pro-inflammatory and anti- inflammatory cytokines. We choosed interleukin 6 (pro-inflammatory) and  interleukin 10 (anti-inflammatory) to study this effect because they are produced  by keratinocytes. Results: our study revealed an increase in serum level of IL6 after treatment with phototherapy.  However no change was observed for IL 10 between basal values and treatment with statistically significant Pvalue for IL-6 statistically insignificant for IL-10.  Conclusions: Phototherapy used in the treatment of neonatal hyperbilirubinemia can affect the level of cytokines but as the previous studies were not homogenous  so more studies are needed to be done to study the effect of phototherapy on serum  cytokines concentration in the newborn
UR  - http://172.23.153.220/th.pdf
ER  -