TY - BOOK AU - Sara Rezk Mahmoud Rezk AU - Maher Fawzy , AU - Mohamed Amr Mattar , AU - Mona Raafat Fahim , TI - A prospective evaluation of different ketofol concentrations for sedation and analgesia in ophthalmic procedures performed under local anesthesia / PY - 2015/// CY - Cairo : PB - Sara Rezk Mahmoud Rezk , KW - Ketofol KW - Ophthalmic procdures KW - Sadation N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anaesthesia; Issued also as CD N2 - This current study suggests that ketofol (ketamine / propofol) concentration at ratios 3:1 and 4:1 may provide effective and safe sedation for patients undergoing ophthalmic procedures under regional anesthesia. An intravenous infusion of a 4:1 ratio is a suitable alternative for delivering ketofol; this provides more stability and consistency of sedation depth and less need for top - up doses that may lead to overshoot of sedation and a delayed recovery. The ratio for the infusion regimen, however, seems best at 4:1 because the overall dose of both drugs required to achieve the same clinical end points is less with a constant infusion, so the ketamine component, which is responsible for the much longer recovery time, can be reduced and a consistent depth of sedation is achieved UR - http://172.23.153.220/th.pdf ER -