Mohamed Yousef Salah <br/><br/>
Obesity-related colorectal carcinoma through insulin resistance, insulin growth factor-1 (IGF-1) And IGF binding protein-3 (IGFBP-3) and their genetic polymorphism /  
 العلاقة ما بين السمنة وأورام القولون السرطانية من خلال مقاومة الأنسولين و معامل نمو الأنسولين رقم  والبروتين الرابط رقم  و الاختلال الجيني لهم  
Mohamed Yousef Salah ; Supervised Ayman Yousry Abdelrahim , Mohammad Salah Abdelbary , Sherif Hamdy 
 - Cairo :   Mohamed Yousef Salah ,   2015 
 - 104 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine 
<br/><br/> In Egypt, CRC represents about 4% of total cancers in both sexes. Variation in  environmental risk factors particularly the higher content of dietary fibers, more  physical activity and lower obesity rates can explain for the different incidence  rates between Egypt and the western countries .      The increased IGF-I bioavailability may, over time, increase the risk of colorectal  cancer. This new evidence for biologic interactions among insulin, IGF-I, and  IGFBPs in the context of colorectal carcinogenesis provides a potential mechanism  through which diet and associated factors may increase the risk of this cancer   
<br/><br/>
<br/><br/><label>Subjects--Index Terms: </label>Binding Protein-3  Colorectal Carcinoma  IGF-1