TY  - BOOK
AU  - Mohamed Yousef Salah
AU  - Ayman Yousry Abdelrahim , 
AU  - Mohammad Salah Abdelbary , 
AU  - Sherif Hamdy , 
TI  - Obesity-related colorectal carcinoma through insulin resistance, insulin growth factor-1 (IGF-1) And IGF binding protein-3 (IGFBP-3) and their genetic polymorphism / 
PY  - 2015///
CY  - Cairo : 
PB  - Mohamed Yousef Salah , 
KW  - Binding Protein-3
KW  - Colorectal Carcinoma
KW  - IGF-1
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine; Issued also as CD
N2  - In Egypt, CRC represents about 4% of total cancers in both sexes. Variation in  environmental risk factors particularly the higher content of dietary fibers, more  physical activity and lower obesity rates can explain for the different incidence  rates between Egypt and the western countries .      The increased IGF-I bioavailability may, over time, increase the risk of colorectal  cancer. This new evidence for biologic interactions among insulin, IGF-I, and  IGFBPs in the context of colorectal carcinogenesis provides a potential mechanism  through which diet and associated factors may increase the risk of this cancer
UR  - http://172.23.153.220/th.pdf
ER  -