TY  - BOOK
AU  - Ahmed Shokry Ahmed Emara
AU  - Hassan Elgarem , 
AU  - Ibrahim Mostafa , 
AU  - Mohammed Ibrahim , 
TI  - Role of second generation ultrasound contrast agent sonovue in the assessment of focal liver lesions / 
PY  - 2015///
CY  - Cairo : 
PB  - Ahmed Shokry Ahmed Emara , 
KW  - Contrast enhanced ultrasound
KW  - Hepatic focal lesions
KW  - SonoVue
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Medicine- Department of Tropical Medicine; Issued also as CD
N2  - Characterisation of a focal liver lesion requires the assessment of morphological characteristics as well as the vascularity and enhancement patterns within the lesion. Therefore, the administration of a contrast agent, demonstrating the intratumoural vascularity and blood flow, gives essential information for the characterisation of focal liver lesions  AIM:The aim of this study was to assess the role of contrast enhanced ultrasound (CEUS) using SonoVue for the characterisation of solid hepatic focal lesions.  METHODS:This prospective study was conducted on 100 patients with hepatic focal lesions. CEUS using SonoVue, in addition to triphasic CT abdomen and/or dynamic MRI were done to all patients.   RESULTS:In the differentiation between benign and malignant hepatic focal lesions; the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of CEUS using SonoVue was 87.8%, 97%, 98.5%, 78.1% and 90.7% respectively, and for CT and/or MRI it was 90.5%, 90.9%, 95.7%, 81.1%, 90.7% respectively. There was no statistically significant difference between CEUS and CT and/or MRI in the characterisation of hepatic focal lesions (p>0.05).  CONCLUSION: CEUS using SonoVue is comparable to CT and/or MRI in the characterisation of hepatic focal lesions
UR  - http://172.23.153.220/th.pdf
ER  -