TY  - BOOK
AU  - Raafat Hassan Mohamed Saleh
AU  - Azza Farrag , 
AU  - Soliman Ghareeb , 
AU  - Wafaa Elaroussy , 
TI  - Assessment of left ventricular mechanical dyssynchrony in  patients with severe mitral regurgitation of rheumatic etiology / 
PY  - 2015///
CY  - Cairo : 
PB  - Raafat Hassan Mohamed Saleh , 
KW  - Dyssynchrony
KW  - Mitral Regurgitation
KW  - Rheumatic
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Cardiology; Issued also as CD
N2  - The degree of left ventricular mechanical dyssynchrony in patients with severe mitral regurgitation of rheumatic etiology is not well  known. Echocardiographic methods have been used to assess LV  mechanical dyssynchrony, are still lagging. Results:  There was statistically significant difference between the two groups regarding Ts-SD, Ts-Dif, corrected Ts-SD and corrected Ts-Dif  (p = 0.000). There was statistically significant differences between the  two groups regarding Tmsv16-SD% and Tmsv12-SD% (p = .026 p =  0.027) respectively, and also there was statistically significant difference  between the two groups regarding Tmsv6- SD% (p = 0.017).and Tmsv6  -Dif% ( p = 0.016) . In our study the prevelance of LV dyssynchrony was  [(22.5{u066A})(7 RHD patients from 31 RHD patients)] by using SDI cut-off 8.3% , and the prevelance of LV dyssynchrony was [ (19.4{u066A}) (6 RHD patients from 31 RHD patients)] by using the Yu index cut-off {u02C3}32.6 ms. Pearson's correlation coefficient in RHD patients showed Dyssynchrony parameters: Tmsv16-SD% and Tmsv12-SD% were statistically significant negatively correlated with 2DEF ( r = - 0. 535 P = 0.002) ( r = -5.489 P  = 0.042 ) and with 3DEF ( r = - 5.518 p = 0.020) ( r =-0.255 P = 0.04) respectively., but Tmsv16-SD% was Positive statistically significant  correlated with LVESD (r = 0.471 P = 0.007) with LVESV( r = 0.990 p  = 0.000 ) with EDV3D (r = 0.527 P = 0.002) and with ESV3D ( r = 0.551  p=0.002). Tmsv12 {u2013}SD% was positive statistically significant correlated  with EDV3D ( r = 0.502 P= 0.004 ) and with ESV3D ( r = 0.478 P =  0.002) with PASP ( r = 0.356 P= 0.030 ) with regugitant volume ( r =  0.420 P = 0.013) . 2DEF was Positive statistically significant correlated  with 3DEF (r = 0.409 P = 0.022). Conclusion: this is the first study to demonstrate that in patients with severe MR  due to rheumatic etiology there is left ventricular dyssynchrony. RT3DE and TDl were able to objectively and accurately evaluate LV function and  LV dyssynchrony
UR  - http://172.23.153.220/th.pdf
ER  -