TY  - BOOK
AU  - Reham Mohamed Arafa
AU  - Ali Mohamed Yehia , 
AU  - Samah Sayed Abbas , 
AU  - Sawsan Mohamed Amer , 
TI  - Analytical study on some antimicrobial drugs / 
PY  - 2016///
CY  - Cairo : 
PB  - Reham Mohamed Arafa , 
KW  - Antimicrobial drugs
KW  - Cefquinome  sulfate
KW  - Chlorhexidine acetate
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry; Issued also as CD
N2  - This thesis deals with the analysis of antimicrobial drugs, Cefquinome  sulfate, Chlorhexidine acetate and Ketoconazole.  The pharmaceutical compounds are subjected to some degradation  due to packing, transportation, humidity and usage. Degradation products  produced may affect the pharmacological and toxicological aspects or  bioavailability. Therefore, stability indicating assays of Cefquinome sulfate  has to be investigated to determine if it persist against different conditions.  Recently, multicomponent formulations have also gained a great importance  due to patient{u2019}s compliance, synergistic effects, multiple action and fast  onset of action. Thus simultaneous estimation of co-formulated drugs is an  important part in the field of pharmacy as it save efforts and time of  extraction and separation.  The aim of this work is to develop simple, efficient and selective  methods for quantitative determination of intact Cefquinome sulfate in raw  material, in presence of its degradation products and in pharmaceutical  formulations. Simultaneous determination of Chlorhexidine acetate and  Ketoconazole binary mixture by different analytical methods was also  performed.  These methods could be used for routine work and quality control  analysis of the investigated drugs either in bulk powder or in their  pharmaceutical formulations.  The proposed methods could be used for stability indicating studies of  Cefquinome sulfate in the presence of its degradation products.
UR  - http://172.23.153.220/th.pdf
ER  -