Ahmed Samir Abdulrahman Abdulsamad <br/><br/>
The prognostic significance of the metastatic lymph node ratio versus the number of affected lymph nodes in patients with colorectal cancer stage III undergoing potentially curative surgery /  
 دراسة الأهمية التنبؤية لنسبة الغدد الليمفاوية الإيجابية بالمقارنة مع العدّ الإيجابي للغدد الليمفاوية لسرطان القولون والمستقيم المرحلة الثالثة والتي يتم معالجتها جراحيا  
Ahmed Samir Abdulrahman Abdulsamad ; Supervised Mostafa Abdelhamid Soliman , Mamdoh Hamed Haggag , Tarek Osama Hegazy 
 - Cairo :   Ahmed Samir Abdulrahman Abdulsamad ,   2016 
 - 120 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of General Surgery 
<br/><br/> Many investigators have questioned the prognostic power of the  TNM system in the prognosis of colorectal cancer because of the  possibility of stage migration, and have proposed alternative prognostic  methods, one of those is the lymph node ratio.  55 patients with colorectal cancer stage III who underwent curative  surgery were enrolled in a retrospective cohort study reviewing their  medical charts from medical oncology department between January 2005  and December 2006, and their five years follow up period regarding local  recurrence, metastasis and survival. The prognostic effect of positive  lymph-node ratio (pLNR) on those patients was evaluated in comparison  to the positive number of lymph nodes. The prospective group is enrolled in a Randomized Control Study and  its managed and followed up in the police authority hospital between  January 2014 and August 2015 (20 months).  25 patients with colon cancer stage III were included in the study with  complete open resection of the primary tumour with lymphovascular  resection as much as possible (Complete mesocolic excision) to allow  determination of a valuable ratio of lymph nodes to see its reflection on  prognosis and follow up of these patients for 18 months regarding  survival rate, local recurrences, metastasis and its relation to gained  lymph node ratio versus the affected number of lymph nodes.  In the retrospective group: The total number of harvested nodes  was (652) LNs mean was 11.85 ±7 (range 330, median 10 nodes). In 32  patients (58.2%) resected LNs was less than 12 and in 23 patients  (41.8%) resected LNs was 12 or more        
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<br/><br/><label>Subjects--Index Terms: </label>Colorectal Cancer  Curative Surgery  Metastatic Lymph Node