TY  - BOOK
AU  - Abdulrahman Mohamed Naguib Abouseada
AU  - Bassant Mohamed Abdulhameed , 
AU  - Hala Moustafa Goma'a , 
AU  - Khalda Galal Radwan , 
TI  - Effects of low flow sevoflurane versus low flow desflurane anesthesia on hepatic and renal functions in hepatitis C positive (Child A) patients undergoing laparoscopic cholecystectomy surgery / 
PY  - 2016///
CY  - Cairo : 
PB  - Abdulrahman Mohamed Naguib Abouseada , 
KW  - Desflurane
KW  - Hepatitis C positive
KW  - Sevoflurane
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Anaesthesia; Issued also as CD
N2  - A prospective randomized control study with 68 patients (Child A) (D, n = 34 and S, n = 34). Liver and kidney function tests, plasma alpha Glutathione-S-transferase (Ü-GST), total 24 hours urinary microalbumin and realtime PCR HCV-RNA were assayed. Results: Preoperative and 3rd day postoperatively with S vs D respectively Ü-GST (4.98±1.97 vs 4.27±1.95 ng/ml non statistically significant)and (7.55±2.4 vs 9.48±1.87 ng/ml P = 0.001), HCV-RNA (4.63±0.86 vs 4.35±1.47 log non statistically significant) and (4.52±0.81 vs 4.69±1.22 log P=0.384) and total 24 hours urinary microalbumin (6.36±2.29 vs 6.90±2.97 mg/24 hours non statistically significant) and (55.67±22.67 vs 13.75±9.10 mg/24 hours P=0.001), yet there{u2019}s a statistical significant between results pre and 3rd day post operatively for Ü-GST, HCV-RNA and total 24 hours urinary microalbumin, the only clinical significance was in total 24 hours urinary microalbumin which showed slight microalbuminurea with group S in the 3rd day post operatively. No clinical difference between preoperatively and post-operatively regarding hepatic and renal functions.Conclusion: Slightly better results in every parameter except for microalbuminurea with S. Neither S nor D were clinically superior to the other with respect to liver, kidneys functions and none of them affected the HCV-RNA virus load
ER  -