Correlation of macular thickness changes and microperimetric values in wet age related macular degeneration (AMD) before and after Anti-VEGF injection /
العلاقة بين التغيرات في سمك ماقولة العين وقيم مجال الابصارلماقولة العين في حالات تحلل الماقولة العمري الرطب قبل و بعد حقن المواد المضاده للعامل المحفز لنمو الاوعيه الدمويه الغير طبيعيه
Asmaa Abdalmonaem Mahmoud ; Supervised Ali Mohamed Taha , Omaima Khaled Eyada , Iman Magdy Eissa
- Cairo : Asmaa Abdalmonaem Mahmoud , 2016
- 92 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Ophthalmology
Purpose: The aim of our study is to evaluate the effect of intravitreal bevacizumab on macular anatomical structure and macular function in eyes with wet age related macular degeneration (AMD) Methods: 30 eyes with wet AMD underwent full ophthalmological examination, Amsler grid testing, macular OCT as well as macular microperimetry before receiving loading dose of bevacizumab and after one month of treatment. Topography and Microperimetry overlay was used. The location and stability of fixation were assessed. Results: There was a statistically significant improvement of macular thickness map as well as the best corrected visual acuity (BCVA) but the improvement of macular sensitivity was not significant. There was a significant positive correlation between the baseline visual acuity (VA) of 0.05 or less and the change occurred in VA .There was no significant correlation between the improvement in macular thickness and the change in macular sensitivity. There was no significant correlation between the improvement in visual acuity and the improvement in macular sensitivity. Conclusion: although early diagnosis and proper treatment are essential for the best outcome regarding both structural improvement and restoration of functional vision, there is still a chance for low vision eyes to restore a reasonable vision
Age related macular degeneration (AMD) Microperimetry Optical coherence tomography (OCT)