Guillain baree syndrome : Subtypes, treatment effect and prognosis : A retrospective study in an Egyptian Pediatric Intensive Care Unit /
متلازمة غيلان باري : الانواع: و تأثير العلاج : دراسة بأثر رجعى فى وحدة عناية مركزة للأطفال مصرية
Mona Salaheldin Ahmed ; Supervised Seham Awad Elsherbini , Nora Elsaied Mohammed , Huda Marzouk Mohammed
- Cairo : Mona Salah Eldin Ahmed , 2016
- 92 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
Background: Guillain-Barré syndrome (GBS) is mostly an acute inflammatory demyelinating ascending polyradiculoneuropathy. Aims: to estimate 1) number, age and sex variations of GBS patients, who were admitted to the Cairo University Pediatric Intensive Care Unit in a five-year retrospective study, 2) incidence of other acute flaccid paralysis mimicking GBS, 3) antecedent illnesses preceding GBS and 4) electrophysiological patterns, clinical variants and response to treatment of GBS patients. Methods: this is a retrospective study of all children with acute flaccid paralysis admitted to Cairo University Pediatric Intensive Care Unit between June 2009 and June 2014 Results: This study detected 52/61 cases (85.2%) had GBS. This study detected 10/52 cases (19.2%) were in the first year age group, 30/52 cases (57.7%) were in the age group from 2-5 years and 12/52 cases (23.1%) were in the age group from 6-12 years. This study detected 27/35 upper respiratory infection cases (77.1%) had GBS, 21/21 gastroenteritis cases (100%) had GBS. This study detected 27/52 cases (44.3%) having acute inflammatory demyelinating polyneuropathy and 17/52 cases (29.5%) having acute motor axonal neuropathy. Miller Fisher syndrome was associated in 5/52 cases (8.2%) and Bickerstaff encephalitis was associated in 4/52 cases (6.6%). Improvement occurred in 47/52 cases (90.4%) and 5/52 cases (9.6%) showed slow improvement and prolonged stay