Role of contrast-enhanced perfusion MR imaging to differentiate between recurrent/residual brain neoplasm and radiation necrosis /
دور الرنين المغناطيسي و النضح بوسط التباين في التفرقة بين أورام المخ المرتدّة/المتبقية والآثار المترتبة على العلاج الإشعاعي
Noha Ahmed Kamal Metaweh ; Supervised Amr Osama M. A. Azab , Wael Mokhtar Elmahdy , Ayman Abdelhameed Elbasmy
- Cairo : Noha Ahmed Kamal Metaweh , 2016
- 201 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis
Patients with brain tumor often develop new areas of contrast enhancement on routine follow-up imaging which can be the result of treatment necrosis, tumor recurrence, or a combination of the 2 outcomes. Identifying the etiology of a lesion is of vital importance in neuro- oncology for both diagnosis and treatment planning purposes. Structural imaging is widely used to observe patients with brain tumor but is generally thought to be inadequate for reliably distinguishing between treatment necrosis and tumor recurrence, because both lesion types appear to be grossly similar on imaging. The gold standard for differentiating between tumor recurrence and treatment necrosis is biopsy, which is expensive and involves risks associated with surgery. Therefore, there is an increased interest in neuro- oncology in the development of noninvasive methods that can differentiate between the 2 lesion types