TY  - BOOK
AU  - Shimaa Khaled Sayed
AU  - Dalia Ahmed Dorgham , 
AU  - Somaya Anwar Hussein , 
TI  - Infection in systemic lupus erythematosus (SLE) patients : : Prevalence and risk factors / 
PY  - 2016///
CY  - Cairo : 
PB  - Shimaa Khaled Sayed , 
KW  - Infection
KW  - Risk factors
KW  - Systemic lupus erythematosus
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Rheumatology and Rehabilitation; Issued also as CD
N2  - This work aimed to study the prevalence of infection in patients  with systemic lupus erythematosus (SLE), find out the different  predictors and risk factors for infection in SLE and to correlate infection  with different clinical, laboratory parameters, disease activity scores and  use of glucocorticoids and immunosuppressive drugs.  One hundred patients with SLE, all fulfilling the 2012 SLICC  criteria for the classification of SLE. All patients included in this study  were subjected to full history taking, clinical examination, laboratory  investigations as well as specific investigations directed to diagnosis of  infection, its site and causative organism.  Our results showed that the most common sites of infection in SLE  patients were chest and skin, while the most common type of infectious  organisms was bacteria. Younger age, early disease, cardiac and  pulmonary involvement, high ESR, thrombocytopenia, elevated serum  creatinine, elevated 24-hours urinary proteins, consumed C3 and C4, high  systemic lupus erythematosus disease activity index (SLEDAI) score and  use of cyclophosphamide (CYC), mycophenolate mofetil (MMF) and  high dose of glucocorticoids (GC), all were associated with increased risk  of infection in SLE patients. Hydroxychloroquine (HCQ) use was  negatively associated with infection
ER  -