Effect of T2DM in inducing changes in visfatin level and deterioration in cardiac function /
ض اي اع ا إاث ى ا ور و ا
Marwa Abdeltawab Mohammed ; Supervised Mohammed Mansour , Dina Abdelfatah , Khalid Refaat
- Cairo : Marwa Abdeltawab Mohammed , 2016
- 126 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Physiology
Background: Diabetes melitus is one of the most nutritional disordes associated with cardiovascular diseases .Visfatin is a new adipocytokine which is largely secreted by visceral adipose tissue and its effects in the development of diabetes and inflammatory reactions are similar to insulin. It acts synergistically with insulin in increasing glucose uptake, stimulating glucose transfer to the muscle and adipose tissue.Methods:Glucose ,lipid profiles, visfatin ,ejection fraction were measured for 31 diabetics and 20 healthy people using usual biochemical methods,echocardiography for ejection fraction and sphygmomanometer for measurement of arterial blood pressure .Results: The mean of body mass index,visfatin, total cholesterol, triacylglycerols, LDL-C and the fasting blood sugar levels,arterial blood pressure were highly significant in the diabetics as compared to those in the controls,whilethe mean HDL-C concentration and ejection fraction were significantly lower in diabetics than in controls.