TY  - BOOK
AU  - Emad Sayed Ewis 
AU  - Doaa Mohammad Abdelatty Ghaith , 
AU  - Mona Abdelaziz Wassef , 
AU  - Walaa Aboulkasem Ismail Shahin , 
TI  - Rapid detection of carbapenemase producing enterobacteriaceae using chromID® CARBA agar  / 
PY  - 2016///
CY  - Cairo : 
PB  - Emad Sayed Ewis , 
KW  - Chrom ID CARBA AGAR
KW  - CRE
KW  - Rapid detection
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology; Issued also as CD
N2  - With the increase in the use of carbapenems, the number of resistant  bacteria with different resistance mechanisms is rising. Some resistance  mechanisms include deactivating antibiotics, altering or producing excessive  amount of drug target receptors by protein gene mutation, acquiring a new  gene that produces insusceptible target, reducing the permeability of cell  membrane to antibiotics and also removing active drug from periplasm or  from inside of cell. Among the most important resistance mechanisms against  carbapenem is producing carbapenemase  The increased worldwide spread of carbapenem-resistant Enterobacteriaceae (CRE) emphasizes the need for a sensitive screening  procedure to identify these microorganisms.Gastrointestinal carriers may serve as the reservoir for cross-transmission in the health care setting, and  thus active surveillance is a key part in preventing the spread of such strains.Method: in our study a new Chrom ID CARBA AGAR (Biomerieux) was used for rapid detection of CRE cases in different departments of Abo elreish hospital. Results and conclusion: It was found that the prevalence of CRE carriers is 70 % in different departments. The sensitivity of Chrom ID  CARBA AGAR was 100 % and the Specificity was 80 %
ER  -