Tamer Samy Mohamed

Isolation and identification of chemical constituents of Caesalpinia species and their evaluation for antimicrobial activity / فصل وتعريف بعض المكونات الكيميائية من نبات السيسالبينا وتقييمهم كمضاد للكائنات الدقيقة Tamer Samy Mohamed ; Supervised Laila Abdelghany Refahy , Magda Ahmed Abdulla - Cairo : Tamer Samy Mohamed , 2016 - 158 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry

The present study was undertaken to isolate and identify of chemical constituents of two Caesalpinia species by chromatographic methods and to determine antimicrobial, antioxidant and cytotoxic activities of the extracts of this ayurvedic plant. Antimicrobial activity was tested against Staphylococcus aureus (G+ve bacteria), Pseudomonas aeruginosa (G-ve bacteria), Candida albicans (yeast) and Aspergillus Niger (Fungi) by Disc agar plate method. Antioxidant activity was determined by DPPH free radical scavenging assay, ferric reducing assay and total antioxidant capacity. Cytotoxic activity was evaluated via using preliminary brine shrimp lethality test and toward liver cancer cell line; HepG2. The results of the biological activities showed promising activities for some of the isolated compounds



Antimicrobial Caesalpinia Chromatographic isolation