TY  - BOOK
AU  - Riham Farouk Gabr
AU  - Amira Mohamed Raafat , 
AU  - Rasha Ahmed Khairy , 
AU  - Samir Ahmed Shawky , 
TI  - Chromogenic in situ hybridization (CISH) evaluation of human epidermal growth factor receptor 2 (HER 2) gene amplification in invasive duct carcinoma on tissue microarray TMA / 
PY  - 2016///
CY  - Cairo : 
PB  - Riham Farouk Gabr , 
KW  - CISH
KW  - HER 2
KW  - IDC
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology; Issued also as CD
N2  - Human epidermal growth factor receptor 2 (HER2) is an important predictive marker in invasive duct carcinoma (IDC), for selecting anti-HER2 therapy candidates. Forty six IDC cases were tested for HER2 amplification by chromogenic in situ hybridization (CISH) and immunohistochemistry (IHC) on a tissue microarray (TMA). A non cost manual method using pencil tips was used to construct two TMA blocks, where each case was represented by three cores. Comparing CISH and IHC results, it was found that there was 100% concordance between both tests in cases of IHC scores (+3,+1,0), and lesser concordance values in IHC equivocal +2 cases
ER  -