TY  - BOOK
AU  - Muhammed Ali Ramadan Ali
AU  - Amr Mohamed Abdelmoniem , 
AU  - Ismail Abdelshafy Abdelhamid , 
AU  - Said Ahmed Soliman Ghozlan , 
TI  - Synthesis of new heterocycles utilizing enamines precursors / 
PY  - 2016///
CY  - Cairo : 
PB  - Muhammed Ali Ramadan Ali , 
KW  - Hexahydroquinoline
KW  - Michael addition
KW  - Ý- enaminone
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry; Issued also as CD
N2  - The original work of this thesis is composed of three parts. In the first part, a facile and convenient synthesis of an interesting N-(1H-pyrazol-5-yl)-hexahydroquinoline-3- carbonitrile and pyrazolo [4',3':5,6] pyrimido [1,2-a] quinoline-6-carbonitrile derivatives via the  versatile readily accessible cyclic enaminones incorporating pyrazole moiety was accomplished. In the second part, the utility of cyclic enaminones with incorporated pyrazole moieties in the synthesis of different tetrahydro-1'H-spiro [indoline-3,4'- quinoline]-3'- carbonitrile and spiro [indoline-3,7'- pyrazolo [4',3':5,6] pyrimido [1,2-a]quinoline] derivatives. In the third part, the three component reaction of bis-isatins, malononitrile and dimedone or 1.3-dimethylbarbituric acid was investigated in ethanol at reflux in the presence of piperidine and afforded bis(spiro [chromene-4,3'-indoline]-3- carbonitrile) and bis(spiro[indoline-3,5'- pyrano [2,3-d] pyrimidine]-6'-carbonitrile) derivatives, respectively, in excellent yields. The chemical structures of all new synthesized products were confirmed based on the different spectral tools and elemental analysis data
ER  -