TY - BOOK AU - Ola Mostafa Ali Ghoniem AU - Amira Maged Abdelazim , AU - Mona Darhous , TI - Evaluation of the use of Nano bone graft as a regenerative technique in comparison to sub- gingival mechanical debridement in patients with vertical bony defects / PY - 2015/// CY - Cairo : PB - Ola Mostafa Ali Ghoniem , KW - Bone substitutes KW - Nano bone graft KW - Regenerative techniques N1 - Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology; Issued also as CD N2 - Aim of study the objective of this study was to evaluate the clinical & radiographic effects of using bone graft (Nano bone graft) as a regenerative technique in one side with vertical bone defect in comparison to sub-gingival mechanical debridement in the other side. Materials and methods: In a split-mouth study design, 10 patients having bilateral intra-bony periodontal defects with radiographic vertical bone loss and associated probing depth {u2265} 7mm. selected sites were randomly divided into two groups. In group I non-surgical periodontal therapy was done, in group ii, Modified Widman flap with application of Nano-bone graft was done. Clinical and radiographic parameters were recorded at baseline, 3-months and 6-month post-opertavely.Results:Both treatment groups showed a significant probing depth(PPD) reduction, clinical attachment gain, increase bone density 6-month after surgery compared with baseline, however, Nano-bone group showed more bone fill at 3 months when compared to nonsurgical group then it decrease to almost equal to nonsurgical group at the end of the study . Conclusion:the use of Sub-gingival debridement is more advisable than modified Widman flaps and Nano-bone application as it gives the same clinical outcome with less cost and less harm for the patient. Clinical recommendations: Further studies are needed with larger sample size and longer duration to detect the action of Nano-bone graft in the treatment of vertical bony defects in comparison to sub-gingival mechanical debridement UR - http://172.23.153.220/th.pdf ER -