TY  - BOOK
AU  - Noha Gohdan Hussein Abdallah 
AU  - Hisham Ali Shokeir , 
AU  - Maha Rafie Abo-Eittah , 
AU  - Nevien Ahmed Samy , 
TI  - Pulsed dye laser versus combined pulsed dye and Nd : YAG Lasers in the  treatment of plaque type psoriasis  / 
PY  - 2015///
CY  - Cairo : 
PB  - Noha Gohdan Hussein Abdallah , 
KW  - Angiogenesis
KW  - Multiplex
KW  - Nd: YAG laser
N1  - Thesis (Ph.D.) - Cairo University - Faculty of National Institute of Laser Enhanced Sciences - Department of Laser Application in Medical and Biological; Issued also as CD
N2  - Background: Angiogenesis play an important role in the pathogenesis of psoriasis.  Based on selective photothermolysis destruction of dilated blood vessels, a major component of psoriatic dermal papillae, can be achieved upon treatment with vascular  lasers.  Objective: This study was designed to compare the efficacy of a 585 nm pulsed dye  laser (PDL) and its sequential application with Nd: YAG laser for the treatment of plaque psoriasis.  Patients and Methods: Thirty patients with chronic and stable plaque type psoriasis  were included in this study. Patients received seven PDL and combined PDL and Nd: YAG laser treatment sessions at two week-intervals. Clinical evaluation of the studied psoriatic plaques was performed by the modified Psoriasis Area and Severity Index  (mPASI) score and by photographs.  Results: Both types of lasers induced a noticeable decrease in (mPASI) scores. The decrease was statistically significant with combined PDL and Nd:YAG laser versus  PDL alone when compared with baseline (p< 0.05). Some plaques that had received  the combined modality showed complete clearance at the 12th and 14th week. Conclusion: The sequential application of PDL followed by Nd: YAG laser  (multiplex) could be more promising than PDL alone in the treatment of plaque  psoriasis
UR  - http://172.23.153.220/th.pdf
ER  -