TY  - BOOK
AU  - Noha Gamal Abdelsalam Haikel
AU  - Abdeljawad Ali Fahmi , 
AU  - Faten Zahran Mohamed , 
AU  - Fathy Mohamed Abdelgalil , 
TI  - Some biochemical studies on neem : : AzadirachtaIndica / 
PY  - 2016///
CY  - Cairo : 
PB  - Noha Gamal Abdelsalam Haikel , 
KW  - AzadirachtaIndica
KW  - Biochemistry
KW  - Neem
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry; Issued also as CD
N2  - Azadirachtaindica (Neem) has been used traditionally for many centuries. Some impressive therapeutic qualities have been discovered. Our study aims to investigate in vivo antitumor, and antioxidant activities of ethanolic neem leaf extract (ENLE) and its fraction nimbolide, a limonoid present in leaves and flowers of the neem tree (Azadirachtaindica). Also, to study the side effects of ENLE and nimbolide fraction on different organs (liver / kidney). Our results showed that Nimbolide and ENLE showed great increase in life span. Also, they showed a significant decrease in malondialdehyde and nitric oxide and an  increase in catalase, glutathione peroxidase, caspase-3 activities, and cytochrome c concentration. Hence, it may be possible that Nimbolide and ENLE decrease lipid peroxidation level due to their antioxidant effect and enhance apoptosis process. ENLE and nimbolide showed no side effects on liver and kidney. Also, they showed a significant protection for both liver and kidney histopathologically
UR  - http://172.23.153.220/th.pdf
ER  -