TY  - BOOK
AU  - Nehad Mohamad Aly Eldydamony 
AU  - Doaa E. Abdelrahman , 
AU  - Sohair L. Elansary , 
TI  - Further study in biologically active coumarins / 
PY  - 2016///
CY  - Cairo : 
PB  - Nehad Mohamad Aly Eldydamony , 
KW  - Angelicins
KW  - Coumarins
KW  - Photochemotherapy
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry; Issued also as CD
N2  - Further Study in Biologically Active Coumarins  Benzopyrones and furobenzopyrones are significant class of natural compounds isolated mainly from higher plants associated to Rutaceae families. They have a broad range and diversity of biological activities.  Photochemotherapy designates a treatment method in which light of an appropriate wavelength is used to induce a therapeutic response in presence of photosensitizing drug such as PUVA.  In this study, new intermediates and final benzopyrone, furobenzopyrones, tetrahydrobenzofurobenzopyrone and benzofurobenzopyrone derivatives were synthesized and screened for antibacterial and photosensitizing activities. Furthermore, docking study was undertaken to evaluate the binding  affinity and orientation of compounds into the active sites of appropriate  gyrase enzymes, compared with their antibacterial activity
ER  -