Noha Ahmed Abdelaziz Mohamed Osman <br/><br/>
Design and synthesis on novel cannabinoid receptor ligands /  
 تصميم و تشييد لبعض المركبات الجديدة لمستقبلات الاندوكنابينويد 
Noha Ahmed Abdelaziz Mohamed Osman ; Supervised Ashraf H. Abadi , Khaled A. Abouzid 
 - Cairo :   Noha Ahmed Abdelaziz Mohamed Osman ,   2015 
 - 173 Leaves ;   30cm 
<br/><br/>Thesis (Ph.D.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceulical Chemistry 
<br/><br/> Cannabinoid receptor endocannabinoids and enzymes catalyzing their formation and degradation coflectively constitute the endocannabinoid system. The potential modulation of this system for therapeutic gain has become a central focus of research during the last decade. Two cannabinoid receptor subtypes (CB1) and CB2) have been identified, which have variable tissue distribution. The CB1 subtype is mainly localised in the CNS and is the subtype that mediates the psychotropic effects of A⁹-THC 
<br/><br/><label>Subjects--Index Terms: </label>Cannabinoid receptor  Endocannabinoids Enzymes catalyzing