TY - BOOK AU - Samy Abdalla Mehany Habib AU - Darius P. Zlotos , TI - N{u2160}-linked metatonin dimers as bivalent ligands targeting dimeric melatonin receptors / PY - 2014/// CY - Cairo : PB - Samy Abdalla Mehany Habib , KW - Dimeric melatonin receptors KW - N{u2160}-linked metatonin dimers KW - Targeting dimeric GPCRs N1 - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceulical Chemistry N2 - The diverse physiological actions of the pineal neurohormone melatonin are mainly mediated through activation of two G-protein-coupled receptors MT₁, and MT₂. These receptors are known to form homo-and heterodimers with distinct functions and properties opening new perspectives for drug design and drug treatment. The bivalent ligand approach is a common strategy for targeting dimeric GPCRs UR - http://172.23.153.220/th.pdf ER -