TY  - BOOK
AU  - Sarah Saad Fayek Saad Naguib
AU  - Rania Mohammed Hathout , 
AU  - Samar Mansour Holayel , 
TI  - Penetration enhancing hybridized vesicles for the efficient ocular delivery of an anti-glaucoma drug / 
PY  - 2015///
CY  - Cairo : 
PB  - Sarah Saad Fayek Saad Naguib , 
KW  - Acetazolamide
KW  - IOP lowering
KW  - Penetration enhancing hybridized vesicles
N1  - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Technology
N2  - The work in this thesis comprised the use of different hybrids of GRAS (generally regarded as safe) oils and surfactants in order to develop and optimize novel acetazolamide entrapped-vesicular systems aiming at improving its ocular delivery and reaching better therapeutic outcomes in the treatment of glaucoma. Accordingly, the phospholipid/cholesterol bilayer of the vesicles was enriched with hybrids of tween 80, labrasol, transcutol and labrafac lipophile WL in different masses and proportions according to a mixture design viz. D-optimal mixture design
ER  -