TY - BOOK AU - Nada Hany Abdelfattah Abdalah Hegazy AU - Hans Georg Breitinger , AU - Ulrike Breitinger , TI - Nover modulators of neuronal glycine receptors from kava (piper methysticum) root extract / PY - 2016/// CY - Cairo : PB - Nada Hany Abdelfattah Abdalah Hegazy , KW - Kava (piper methysticum) KW - Neuronal glycine receptors KW - Nover modulators N1 - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Biochemistry N2 - The search for new modulators of ligand gated ion channels is a highly significant field of research as specific ligands help to increase our understanding of receptor pharamacology and stracture function relationships. The inhibitory glycine receptor, an anion selective inhibitory ligand gated ion channel (LCIC) and member of the cys-loop reseptor superfamily it found in the spinal cord, brain stem, and higher brain centers such as the forebrain, hippocampus, hypothalamus and medial vestibular neurons in addition to the retine and cochlea ER -