Molecular repair mechanisms-combined effects of gain-and loss-of- function mutants on channel function of the inhibitory glycine receptor /
Mohammad Mamdouh Abdelwareth ; Supervised Hans-Georg Breitinger , Carmen Villmann , Ulrike Breitinger
- Cairo : Mohammad Mamdouh Abdelwareth , 2014
- 98 Leaves : charts , facsimiles ; 30cm
Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Biotechnology
Fast synaptic inhibitory neurotransmission in the central nervous system is principally mediated by -aminobutyric acid type A receptors(GABAAR) and glycine receptors(G1yR). The spinal cord and brainstem are main sites of actionof glycine receptors. Glycinergic synapses are present in spinal cord motor reflex pathways, spinal cord nociceptive ( pain sensory) pathawys.