Reduction of hepatitis C viral replication through targeting HCV-genotype 4p7 Ion channal by MicroRNA-29a /
Radwa Ayman Salah Helmy ; Supervised Ahmed Ihab Abdelaziz
- Cairo : Radwa Ayman Salah Helmy , 2013
- 105 Leaves : charts ; 30cm
Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Molecular Pharmacology
Hepatitis C virus infection (HCV) is a global health crisis, characterized by a virusmediated suppression of the host immune response. It is considered a leading cause of chronic liver disease worldwide. Egypt is considered to have the highest prevalence of HCV globally (17%), where the majority of cases are infected with the " difficutlt-to-treat" genotype 4.p7 is viral protein that acts as an ion channel and has a crucial role in HCV life cycle, rendering it an attractive therapeutic target.
HCV-genotype 4p7 Ion channal Hepatitis C virus infection (HCV) MicroRNA-29a