Epigenetic harnessing of HCV via modulating the lipid droplet-proteins, ADRP and TIP47, in HCV cell models /
Nada Magdy Elekiaby ; Supervised Ahmed Ihab Abdelaziz , Gamal Esmat
- Cairo : Nada Magdy Elekiaby , 2014
- 95 Leaves : charts , facsimiles ; 30cm
Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Molecular Pharmacology
Host cell lipid droplets (LDs), along with their associated PAT proteins (perilipin protein family) contribute to the regulation of numerous cellular processes as well the pathogenesis of various diseases. LDs play an impotant role in promoting the life cycle of hepatitis C virus (HCV). The regulation of PAT proteins expression and subsequently cellular lipid droplets by microRNAs has never been investigated.