In vitro photodynamic therapy of de-pigmented melanoma via liposome-encapsulated chlorophylin derivative /
Aya Ahmed Sebak Mohamed ; Supervised Mahmoud Hashem Abdelkader , Nagia Naguib Afifi , Iman Emam Omer Gomaa
- Cairo : Aya Ahmed Sebak Mohamed , 2014
- 111 Leaves : charts , facsimiles ; 30cm
Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Technology
Cutaneous melanoma has the highest potential to metastasize in all body organs and represents a life threatening disease. Photodynamic therapy (PDT)has proved to be a potential treatment modality in various types of cancerous and non-cancerous diseases. The objactive of this study is to assess the PDT- mediated cell killing in de-pigmented Bi6.F10 melanoma cell line, using liposomes-encapsulated sodium ferrous chlorophylin derivative (FE-CHL)