TY - BOOK AU - Nermin Mohammed Ahmed Yussif AU - Sami Sadek Ismail , AU - Shaimaa Omar Zaid , AU - Shereen Ali Hassan , TI - Evaluation of injectable Vitamin C as a depigmenting agent in physiologic gingival melanin hyperpigmentation : : A Randomized clinical trial / PY - 2016/// CY - Cairo : PB - Nermin Mohammed Ahmed Yussif , KW - Ascorbic acid KW - Depigmenting agent KW - Vitamin C N1 - Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology; Issued also as CD N2 - Objective : Evaluate the efficiency of vitamin C as a depigmenting agent in patients with physiologic gingival hyperpigmentation and assess its clinical and histopathologic effect on the patients{u2019} gingival health.Background data: Gingival melanin hyperpigmentation is an aesthetic problem which concern many individuals. Various surgical and non-surgical approaches have been reported for its management but most of them are associated with hazardous effects. Methods: Forty patients suffering from physiologic gingival melanin hyperpigmentation was included. Intraepidermal injection of vitamin C was repeated once per week until no visible pigmentation. The patients were recalled after 1, 3 and 6 months after treatment for follow up.Results: There is a decrease in pigmentation indices scores and reduction in the area with a significant statistical difference between pre-operative visit and both injection as well as follow-up visits. Regarding gingival health, the results revealed a reduction in mean SBI scores after vitamin C injection and statistical significant improvement of the gingival biotype with shift from the thin gingival biotype to the thick one.Conclusion: Vitamin C injection is a safe, minimally invasive non-surgical depigmenting technique which improves health of gingival tissues UR - http://172.23.153.220/th.pdf ER -